|
KMID : 1161420220250040402
|
|
Journal of Medicinal Food
2022 Volume.25 No. 4 p.402 ~ p.407
|
|
|
Exclusive Enteral Nutrition Remission Induction Treatment Influence on Transient Hypertransaminasemia in Children with Newly Onset Crohn's Disease
|
|
Wasilewska Agata
Ponanta-Gawron Katarzyna
Burtan Beata
Sagaran Charissa Stephen Chandra
Duplaga Mariusz
Kowalska-Duplaga Kinga
|
|
|
Abstract
|
|
|
|
Pediatric Crohn's disease (CD) is commonly associated with hepatobiliary complications, including transient liver enzymes elevation (LEE). Exclusive enteral nutrition (EEN) is recommended as primary treatment in mild-to-moderate pediatric CD. Data concerning EEN and liver enzymes (LE) abnormalities are limited. The aim of this study was to assess the LEE occurrence in newly diagnosed CD pediatric patients during EEN. Retrospective analysis of 73 patients, with no previous signs of liver disease, qualified to EEN. LE were assessed at diagnosis, during EEN, after completion of the nutritional treatment, and reintroduction of free diet. Thirty-one (42%) children presented with LEE and 28 (38%) with transient LEE. The LEE cohort presented with higher percentage of protein energy (24.0%?±?29.4 IQR [interquartile range] vs. 18.6%?±?23.6 IQR, P?
|
|
|
KEYWORD
|
|
|
Crohn's disease, exclusive enteral nutrition, inflammatory bowel disease, liver enzymes, pediatrics
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|